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This epigenetic mechanism is consistent with the broader Khavinson framework for bioregulator peptides, which proposes that short peptide sequences (27 amino acids) can penetrate nuclear membranes and interact directly with DNA or chromatin-associated proteins to modulate tissue-specific gene expression

Studies have also reported that calcitonin gene-related peptide, which is known to play a role in the development of migraine and serves as a therapeutic migraine target, may signal vestibular receptors

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Its unique mechanism of action does not interfere with hormone-related peptides or tissue repair compounds