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Severe diarrhoea and severe vomiting were uncommon with tirzepatide, affecting 0.31% and 0.25% of participants, respectively [8,9,10, 12]

5.4 Interstitial Pneumonitis Serious interstitial pneumonitis, including fatal cases, can occur with pemetrexed for injection treatment

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Lyophilized forms: Both tirzepatide and semaglutide are available in lyophilized form for research purposes, with similar 28-day post-reconstitution stability windows