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This study has been in accordance with the Helsinki Declaration and was approved by the Ethics Committee of Xinhua Hospital, Shanghai Jiaotong University School of Medicine (Approval ID: XHEC-D-2023-142)

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Additionally, data on the real-life use of oxidative stress (OS) testing and AOX use obtained from the largest global survey of practicing physicians conducted by GAF, which served as a reference point for this study

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