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In summary, this glycolysis-centered metabolic reprogramming not only provides essential energy for the abnormal proliferation of leiomyoma cells but also influences the physiological state of surrounding tissues by altering the metabolic microenvironment (such as acidification and lactate signaling), constituting a key mechanism for the sustained growth of uterine fibroids

Novel Biomarkers of Intervertebral Disc Cells and Evidence of Stem Cells in the Intervertebral Disc

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There is increasing evidence indicating that genetic factors, reduced expression of related proteins, and defective vesicular transportation are potential causes of autophagy pathway disruptions