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In our outpatient clinic, high-dose glutathione infusions with other immunomodulators such as mistletoe, thymus, enzymes or cytokines are successfully used, partly supported by other antioxidants such as selenium and vitamins

Collectively, these data raise the possibility that the GSK3-CaMKK2-CaMK4 signalling axis is a principal site of action through which lithium increases BDNF expression and exerts its anti-manic effects