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An isolate of Haemophilus haemolyticus produces a bacteriocin-like substance that inhibits the growth of nontypeable Haemophilus influenzae

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Am J Psychiatry (2013) 170:26574.10.1176/appi.ajp.2012.12050620 178 WeinerMWarrenLFiedorowiczJG

Disclosure of interest: Jessica Seetge: nothing to disclose, Balzs Cske: nothing to disclose, Zsfia Nozomi Kardi: nothing to disclose, Edit Bosnyk: nothing to disclose, Lszl Szapry: nothing to disclose E-Posters - RECOVERY, REHABILITATION AND OUTCOME 03.00 - RECOVERY, REHABILITATION AND OUTCOME - 03.02 - LIFE AFTER STROKE P2180 - ESOC25-73 FACTORS ASSOCIATED WITH POST-STROKE MOOD DIFFICULTIES ASSESSED USING THE STROKE IMPACT SCALE-64 IN MULTI-ETHNIC POPULATION Min Sun Kim 1 , L Brian Hickman 2 , Katherine Mun 2 , Nerses Sanossian 3 , Sidney Starkman 2 , Gilda Avila-Rinek 2 , Latisha Sharma 2 , David Liebeskind 2 , Robin Conwit 4 , Scott Hamilton 5 , Jeffrey Saver 1 Brigham and Women's Hospital, Boston, United States, 2 UCLA Medical Center, Los Angeles, United States, 3 USC Medical Center, Los Angeles, United States, 4 National Institute for Neurological Disorders and Stroke, Bethesda, United States, 5 Stanford University, Palo Alto, United States Background and Aims: Studies on predictors of post-stroke mood difficulties have shown inconsistent results, in part due to limitations in mood/depression scales in stroke patients

This, in turn, increases the level of mtDNA in the cytoplasm and directly activates the cGAS/STING pathway, promoting the production of inflammatory factors