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When cells experience oxidative stress, PARPs consume NAD+ for DNA repair [11]

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Conclusions The polymorphic genes analysed here may have a role in the susceptibility of patients affected by vitiligo, while little is known about the affected workers, due to the lack of epidemiologic data on these subjects

Collectively, these findings suggest that targeting PARP1 may represent a promising strategy against fatty liver disease by mitigating inflammation, oxidative stress, and fibrosis