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This revelation compels a deeper understanding of their influence on the disease's onset and progression

Cystine deficiency has been shown to promote the development of ferroptosis in numerous cancer cells, indicating that it may be a treatment target in breast cancer (18)

Similarly, sodium selenite, a widely used experimental cataract-inducing agent, suppresses Nrf2-dependent antioxidant protection while facilitating lenticular protein oxidation and cataract formation (246)

CB-839 also significantly reduced the conversion of glutamine to glutamate at 10 nM for the HG-3 cell line and at 1 M for the MEC-1 cell line after 72 hours of incubation