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Caino MC, Ghosh JC, Chae YC et al (2015) PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion

Silver Spring Md, vol

This dysregulation is secondary to mutations in elements of the pathway that include the APC gene (adenomatous polyposis coli), -catenin, or other elements, which make the pathway to be constitutively active and has oncogenic consequences [118, 119]