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When the excitation wavelength was set as 365 nm, in normoxia, no obvious fluorescence peak was observed in the spectrum of the probe DSNBD-GSH (10 M), while the incubation with GSH (1 mM) led to the appearance of a notable fluorescence peak at 478 nm (Supplementary Figure S7B)

Samples were then treated with conventional grades of alcohol (70%, 80%, 90%, and 100%) to remove the water within tissues

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It improves skin quality but does not specifically treat pigmentation

Both RH-PLGA and RH-PLGA/chitosan caused minimal tissue disruption