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Model building and refinement The structure model of apo-form ABCC2 was built based on an initial model predicted by AlphaFold2 52 and refined with secondary structure and geometry restraints, automatically or manually using Real-space refinement in PHENIX 1.20.1 53 or WinCoot 0.9.8.1 54

Some research studies have used higher doses for specific conditions, but high doses should only be taken under the supervision of a healthcare provider

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Yes, it's often combined with Vitamin C injections to enhance antioxidant effects

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