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There are virtually no adverse side effects

From these initial runs, we determined that GR was significantly more active, and the system was more efficient at scavenging ROS if Gpx concentration was higher than GR concentration

These specialized protein complexes, composed of claudin, occludin, and zonulin, among other molecules, form a seal in the paracellular space between adjacent IECs, thereby tightly controlling the passage of ions and solutes (165)