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The volume of distribution and the half-life need not be known in order to determine the average plasma concentration expected from a given dosing rate or to predict the dosing rate for a desired target concentration

Following the emergence of MDM2 as a p53 inhibitor, pharmacological disruption of the interaction between these two proteins has been explored to reactivate p53 in human tumors that express wild-type TP53

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10.21037/jtd.2019.05.10 J Thorac Dis

Hydration is crucial in the morning to replace the minerals you lost overnight just from breathing and sleeping