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In summary, CoQ10 supplementation has demonstrated considerable potential in enhancing female fertility, particularly by improving ovarian function, increasing egg quality, and mitigating inflammatory responses (Figure 2)

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Future researches are needed to integrate multiple omics approaches to analyze the spatiotemporal dynamics of mtDNA mutations and develop precise delivery systems for targeted interventions

Iglesias-Aguirre CE, Romo-Vaquero M, Victoria Selma M, Carlos EJ