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10.1073/pnas.2534397100 Proc

doi: 10.1016/j.humimm.2007.10.011 56 LauricellaMCarlisiDGiulianoMCalvarusoGCernigliaroCVentoRet al

Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-beta42 by LRP1-dependent apolipoprotein E isoform-specific mechanism

doi: 10.1007/s10350-004-6251-8 58 TomitaR.TanjohK.FujisakiS.IkedaT.FukuzawaM

This process relies on KLF1 (Krueppel-like factor 1), FOXO3 (forkhead box O3), and E2F2 transcription factors, chromatin condensation-regulating caspase-3, DNA methylation-regulating Tet family proteins, Asxl1, cytoskeleton-regulating Rho GTPases, and p38 MAPK signaling [51, 52]