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Abstract Introduction: It has been proposed that an increased susceptivity to oxidative stress caused by the absence of the protein dystrophin from the inner surface of the sarcolemma is a trigger of skeletal muscle necrosis in the destructive dystrophin deficient muscular dystrophies

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doi: 10.1038/nrrheum.2017.49 24 NiSYuanYKuangYLiX

Similarly ERs could potentially be involved in the anti-oxidant gene expression involving Nrf2 through recruiting co-regulatory proteins