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A subpopulation of B cells known as Bregs is essential for preserving immunological tolerance and limiting excessive inflammation

This is especially important in neurological disorders as the BBB is a formidable obstacle to the systemic treatment of CNS diseases, because it impairs the passage of the vast majority of molecules, including antibodies, to the brain

Results: Fourteen patients were enrolled (cell transplant group: 10, standard treatment group: 4)

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Unlike single-compound nootropics that target one neurotransmitter pathway, Cerebrolysin delivers a cocktail of bioactive peptides that mimics the effects of several endogenous growth factors simultaneously