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10.1016/j.biochi.2012.01.023 67 KurakulaM.NaveenN

Cycle 14 (18), 28812885

Neuropathologically speaking, PD is a gradual death of dopaminergic neurons in the dense region of the SN, typically accompanied by the formation of Lewy synapses and intra-neuronal Lewy bodies

In high SDI areas, deaths rose from 738.25 (95% UI, 106.45 to 1,834.60) in 1990 to 2,017.36 (95% UI, 300.32 to 5,033.64) in 2021 (a 173.26% increase, 95% UI, 148.00189.93), while in low SDI areas, deaths increased from 150.26 (95% UI, 23.48 to 411.07) to 521.94 (95% UI, 82.57 to 1,375.40), representing a 247.35% increase (95% UI, 185.47357.45)