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It has been extensively studied for its role in skeletal muscle differentiation and the regulation of glucose metabolism 168 (Fig

In this single study, researchers hypothesized that elevated serum selenium levels and reduced copper levels in patients with HTs and overt hypothyroidism might result in lower L-thyroxine dosages or reaching a euthyroid state with decreased free T4 due to the direct impact of the copper-selenium ratio on redox balance and as a result of thyroid health [109]

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