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Fufang-zhenzhu-tiaozhi formula (FTZ), a patented TCM preparation, has been demonstrated to promote -cell regeneration by protecting the islets from inflammatory cell invasion, maintaining the number of pancreatic -cells, and increasing the expression of key markers of new -cell formation, such as PDX-1, MAFA, and NGN3 ( Puerarin has demonstrated a significant improvement in blood glucose homeostasis in HFD-induced diabetic mice

By contrast, the p53(4KR98) mutant, with an additional lysine 98 substitution, does not downregulate SLC7A11 (8587)

Pathways and regulation of homocysteine metabolism in mammals

Podkowiska A, Formanowicz D (2020) Chronic kidney disease as oxidative stress-and inflammatory-mediated cardiovascular disease

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