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It has also been suggested that the immune dysfunctions seen in ME/CFS could be a reflection of the pervasive adrenergic hyperstimulation (Scanzano and Cosentino, 2015

In parallel, it exhibits antiinflammatory actions by suppressing microglial activation and downregulating proinflammatory cytokines such as IL1 and TNF, attenuating the chronic neuroinflammation implicated in neuronal degeneration (Yang et al