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In addition, the possibility to manipulate SLC25A39 and/or to regulate the amount of GSH that enters mitochondria also offers the opportunity to study the importance of mitochondrial GSH in more detail, especially in mitochondria-rich tissues like liver or kidney

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Disruptions in the Grx system have been linked to the development and progression of various oxidative stress-related diseases, highlighting its importance in cellular redox balance and signaling pathways 57

The most beneficial effect was noted for embryos isolated from seeds subjected to artificial ageing for 14 and 21 days