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Following the established SUPPA2 pipeline 46 (Methods), we assigned relative abundances of the splicing events or transcript isoforms (referred to as proportion spliced-in (PSI) 47 ) for each transcript across all three timepoints, under four different conditions: T-REX (NCBP1-HNEylation) and three controls (DMSO-alone, light-alone or probe-alone treatment)

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Tanaka K, Masaki Y, Tanaka M et al (2014) Exenatide improves hepatic steatosis by enhancing lipid use in adipose tissue in nondiabetic rats

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Insulin promoting the growth and proliferation of cells is one of the mechanisms underlying increased cancer risk in obese and diabetic patients (119, 120)