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This Review aims to help researchers make informed decisions when choosing an experimental design that best aligns with the specific requirements of their projects, whilst meaningfully replicating human disease

Oxidative stress can break down collagen, leading to skin laxity

longum 5(1A) administration in the dextran sulfate sodium- (DSS-) induced colitis in mice abated severe lesions in the colon with the decreased level of eosinophil peroxidase [40] (Figure 1)

This process, through the use of sulfur-containing compound such as glutathione, taurine, and SAMe, helps to detoxify sulfur-containing chemicals found in food additives, drugs, and the environment, all of which can be potentially harmful to the body

While initially adaptive, prolonged or severe ER stress leads to excessive ROS production, further exacerbating cellular injury (Zhang et al., 2025)