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Garlic extract supplementation (10 mg/day) for four days did not significantly alter single-dose pharmacokinetics of the protease inhibitor, ritonavir (Norvir), but further research is needed to determine steady-state interactions between well-characterized garlic supplements and ritonavir (160)

The definition of vitamin B12 deficiency varies with the assay used but generally includes serum cobalamin levels below 148 pmol/L plus symptoms, or elevated serum homocysteine, or increased methylmalonic acid (MMA) (74)

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pyogenes (HKU16 gshT strain), showed expression changes in 165 genes

Comprehensive Preclinical In Vivo Data: Before initiating human studies, a preclinical programme of in vivo studies in animal models is crucial to assess the safety and efficacy of the drug candidate