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The immune system mistakenly attacks the joints, leading to inflammation and tissue damage

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Increasing evidence suggests that microbial infection may also contribute to RA development, with Porphyromonas gingivalis , Proteus mirabilis , and Mycobacteria among the bacterial species with potential aetiological roles (Li et al

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Type II collagen-chondroitin sulfate-hyaluronan scaffold cross-linked by genipin for cartilage tissue engineering