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138 Furthermore, MCD, as a commonly used model for inducing CLD and even HCC, is closely link to cancer

Ohmoto, A

For individuals following plant-based diets, fortified foods (such as breakfast cereals, plant-based milk alternatives, and yeast extracts) or supplements become essential sources

Of note, the metabolic effects were attributed to butyrate serving as energy substrate and not butyrate acting as inhibitor of HDAC activity 93 , which has been reported to inhibit proliferation of colonic ISCs via Foxo3 116

Proc Natl Acad Sci USA 90(15):72407244 Snchez-Pernaute R, Ferree A, Cooper O, Yu M, Brownell AL, Isacson O (2004) Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease