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Their loss accelerates the disease course and skews to a Th1-type response

During excitation-contraction coupling, Ca 2+ emitted from the sarcoplasmic reticulum is transmitted into the mitochondrion

Lipid peroxidation and total glutathione in the central nervous system increased in response to vitamin E deficiency, serving as histological and molecular markers of oxidative stress

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The relationship with HOX will be relevant in areas where HOX are expressed, notably the posterior SHF (Stefanovic et al, 2020) and Juxta-cardiac field (JCF) (Tyser et al, 2021)