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Certain conditions, such as severe kidney or liver disease, may contraindicate the use of these treatments

Many studies have proven the efficacy of restricted radiation areas on reduced gastrointestinal side effects as well as enhanced dose tolerance in radiotherapy ( b) Dose-Volume Effect Radiation-induced digestive injury manifests as a dose-volume effect, meaning that the extent of the lesion highly depends on the radiation dose and radiated volume (3443) and precisely predicted (44)