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16 The metabolic disorders cause a variety of complications

Some signs that your child could benefit from growth hormone therapy include: A slow growth rate : Less than 2 inches of growth per year after the age of 3 Short stature : Height significantly below the average for their age and gender Delayed puberty : Lack of puberty-related changes such as growth of pubic hair, breast development in girls, or muscle mass in boys Excess body fat , particularly around the waist and face Fatigue , weak muscle tone , or low energy levels If you notice these symptoms, it is important to consult a pediatric endocrinologist or hormone specialist who can assess your childs growth patterns and recommend the best course of treatment

31 along with the analysis of Table 6 and Fig

Caggiano C, Pieraccioli M, Pitolli C, Babini G, Zheng D, Tian B, et al