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(39407841) overall epidemiology Pyroglutamic acidosis is rare, with only ~130 reported cases in the literature

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ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Moreover, in vitro and in vivo , which in turn, induced FoxO1 and thereby upregulates the gluconeogenic genes G6pc (glucose-6-phosphatases), pck1 (cytosolic phosphoenolpyruvate carboxykinase) in the liver, leading to hyperglycemia