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Here, we identify that LCN2 promotes intracellular iron accumulation, mitochondrial dysfunction, and lipid peroxidation through its receptor SLC22A17, and drives ferroptotic cell death

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CD44 ligands and interacting molecules CD44 binds to several ligands including hyaluronic acid (HA), osteopontin (OPN) [23], chondroitin [24], collagen [25], fibronectin [26], and serglycin/sulfated proteoglycan [27]