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To achieve blood levels of at least 30 ng/mL, adults living at temperate latitudes (think: anywhere with distinct seasons) need 800 to 1,000 IU per day, ideally from vitamin D3, which is more effective than D2

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After binding to ACE2 and/or NRP1 receptors, the S-protein is proteolytically pre-activated by human proprotein convertase furin 66

Although various studies have emphasized the importance of necrosis and apoptosis, the current paradigm acknowledges various cell death pathways