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Description

Science 70 , 381382 (1929)

Tumor cells were treated with tBHQ, the quinone radical of which is an electrophile that covalently modifies cysteine residues in KEAP1 preventing it from targeting NRF2 for degradation

Similarly, CAT activity was significantly reduced in the roots of plants treated with GSH, whereas no significant difference was found in the leaves compared with the Cd-only treated plants (Figure 4B)