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Potential Research Applications: Fat Metabolism: In obese animal models (e.g., Zucker rats), AOD 9604 reduced body weight gain by over 50% within 19 days (oral, 500 g/kg daily)

Low B12 has been associated with sleep disturbances and with mood symptoms such as low mood or anxiety, and correcting a confirmed deficiency may help some people in these areas

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Discuss use with your clinician if you take glucose-lowering drugs, blood-pressure medicines, stimulants, or other weight-loss agents

A recent screening-based study has identified several promising SARM1 inhibitors, including non-competitive inhibitors such as berberine chloride and zinc chloride 233 , suggesting the presence of an allosteric binding pocket that can be targeted for therapeutic development