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4614-C DOWNREGULATION OF SOX9 MEDIATED BY REDUCED NOTCH AND HIPPO SIGNALING RESULTS IN BILE DUCT PAUCITY AND IMPAIRED DUCTULAR REACTION IN AN iPSC-DERIVED, HUMAN, THREE-DIMENSIONAL MODEL OF ALAGILLE SYNDROME Marie-Agns M'Callum, Silvia Selleri, Quang Toan Pham, Alexandre Archambault-Marsan, Kristen Vieira-Lomasney and Massimiliano Paganelli, CHU Sainte-Justine, Universit De Montral Background: Alagille syndrome (ALGS) is an autosomal dominant multisystemic disease resulting in bile duct paucity, cholestasis and progressive fibrosis

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On the other hand, upregulated glucose metabolism was reported to favor apoptosis of infected CD4 + T-cells (Hegedus et al , 2014)

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Macleod SL, Nowell S, Plaxco J, Lang NP: An allele-specific polymerase chain reaction method for the determination of the D85Y polymorphism in the human UDP-glucoronosyltransferase 2B15 gene in a case-control study of prostate cancer

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These included: simple update (consumption reported on the most recent FFQ before each follow-up interval)

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