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Complement activation and disease: protective effects of hyperbilirubinaemia

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However, as discussed above, orally administered T does not induce the expression of CYP or membrane transporters ( Reference Podszun, Grebenstein and Hofmann 37 , Reference Hundhausen, Frank and Rimbach 55 , Reference Kluth, Landes and Pfluger 56 , Reference Leonard, Joss and Mustacich 58 ) , rendering this mode of interaction rather unlikely

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Early stages of POAG are asymptomatic and the emerging disease can be recognized only using sophisticated biomarker-based approaches 9,10