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According to this study, the likelihood of having MASH increased by 30% for every 50 U/l increase in CK-18 plasma levels (OR = 1.3, 95% CI: (1.1, 1.4)

The first necessary step is the enzymatic removal of the glutamic acid residue from the glutathione-Mercury(II) conjugate to yield the Mercury(II)-cysteinyl-glycine conjugate