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Particularly, peptides are often used to synthesize biocompatible and functional metal nanoclusters due to its special three-dimensional structure, adjustable sequence, convenient synthesis and economical price 33

Bilirubin as a metabolic hormone: the physiological relevance of low levels

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These types of aptasensors are operated based on three major principles, such as fluorescence signal amplification (FSA), fluorescence resonance energy transfer (FRET), and fluorescence polarization (FP) as shown in Table 3