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In this study, we found that morphine effects were also reversed by CB 1 receptor antagonist treatment which confirms previous findings by Yamaguchi et al

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TNF-TNFR2 interactions are critical for the development of intestinal graft-versus-host disease in MHC class II-disparate (C57BL/6JC57BL/6Jbm12)F 1 mice

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Moreover, this effect is combined to a downregulation of the expression of senescence-associated cytokines in the second model and an improvement of mice physical condition in the third model, respectively 37