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and Appl

62 FuruhashiS.SugitaH.TakamoriH.HorinoK.NakaharaO.OkabeH.et al (2012)

Thalidomide analogs (also known as immunomodulator imide drugs, IMiDs)anti-cancer agents that function through this mechanismresurface the E3 substrate receptor, CRBN, to induce the recruitment, ubiquitination, and degradation of neo -substrate targets, including therapeutically important transcription factors 1019