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Nevertheless, multiple clinical trials testing different cyclic dinucleotides [e.g., BMS-986301 (NCT03956680) or BI 1387446 (NCT04147234)] either alone or in combination with other cancer therapies are currently ongoing and will ultimately determine the future relevance of STING agonists in a clinical setting (www.clinicaltrials.gov)

The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence

Side Effects and Risks For a healthy adult getting a routine drip from properly trained staff, IV therapy is usually well tolerated

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Apply on clean, dry skin