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Yang et al., 2024

Hypercholesterolemia occurs in 1660%, whereas hypertriglyceridemia is reported in 736% of cases [269, 270]

Kluczowe zastrzeenie: zdecydowana wikszo tych danych pochodzi z bada na szczurach i myszach oraz z bada in vitro

Ethical approval This study was conducted under the guidelines of the National Council for the Control of Animal Experimentation (CONCEA) and was approved by the Ethics Commission for Animal Use (CEUA) at Instituto Federal do Rio Grande do Sul campus Serto, RS, Brazil (Protocol number 1806240222)

Decades of research in pursuit of such a singularity has, however, uncovered common themes between select subgroups of mutant proteins, which may collectively be predictive of the propensity for all mutant proteins to misfold