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At the molecular level, AOD-9604 interacts with beta-3 adrenergic receptors on adipocytes (fat cells), triggering a signaling cascade that increases intracellular cyclic AMP levels

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Cultures were supplemented on days 0, 1 and 2 with 5 mM NaCl or 5 mM BHB

Vedeck referencie Seiwerth et al

Low albumin levels cause fluid in the blood to pass into the tissues, producing swelling not only of the legs and feet, but also other parts of the body such as the hands and face