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Mol Cancer Ther 5(3):575585 Bishopric NH, Webster KA (2002) Preventing apoptosis with thioredoxin: ASK me how

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And circ P4HB could regulate SLC7A11 by regulating miR-1184 to trigger GSH synthesis, which can protect lung cancer cells from erastin-induced ferroptosis, and promote tumor growth in vivo [163]

The minimalist anticodon recognition of the aaRS to its tRNA makes it possible to mutate the aaRS amino acid binding pocket from tyrosine to an UAA with little loss of affinity and aminoacylation efficiency of the aaRS for the tRNA (Steer and Schimmel, 1999)

For instance, the CPT1A inhibitor Etomoxir has not been widely used in cancer clinical trials