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Approach Phase 2b trial arm Duration 24 weeks Review Point Week 12 and 24 Notes METAOD006 (OPTIONS) used 24 weeks at oral doses 0.25, 0.5, or 1 mg/day in 502 obese adults

If you are considering starting B12 supplements, particularly at high doses, discuss this with your GP or a registered pharmacist, especially if you have existing medical conditions or take other medications

For athletes, its also important to note that AOD9604 is currently prohibited by the World AntiDoping Agency (WADA), meaning competitive sports users could risk antidoping violations

Some people also have difficulty absorbing vitamin B12 as a result of bariatric surgery, pernicious anemia, obesity, Imerslund-Grsbeck disease, Addisons disease, or an intrinsic factor deficiency (12)

Frequently Asked Questions Does vitamin B12 help with stress