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Results: 1828 patients (median age 52 (42-60) years, 61% male, 51% with alcohol-related CLD) were studied: 447 (24%) with AD, 319 (17%) with ACLF1, 407 (22%) ACLF2 and 655 (36%) ACLF3 on admission

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This effect may be related to the activation of AMP-activated protein kinase (AMPK) and sirtuin1 (SIRT1)/forkhead box O1 (FOXO1) pathway (Li et al., 2018

Feng Y, Zhao X, Lv F et al (2015) Optimization on preparation conditions of salidroside liposome and its immunological activity on PCV-2 in mice

6.3 Gaps in African cancer epidemiology and research priorities The evidence reviewed above highlights substantial knowledge gaps limiting our understanding of diet-cancer relationships in African contexts: Prospective cohort studies: Africa has few large-scale prospective cohorts following populations with detailed dietary assessment over decades to definitively establish causal relationships between specific food exposures and cancer outcomes