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The compound is commonly used in metabolic research exploring mechanisms of appetite signaling, insulin pathway modulation, and cellular energy regulation

Febuxostat is approved by the FDA to start at 40mg daily, and if the uric acid has not reached goal (less than 6.0mg/dL) after two weeks of treatment the dose can be increased to 80mg daily

a two-way ANOVA with repeated measures indicated that all time points for the I nmol dihexa group were different from the scopolamine group, which received vehicle (aCSF) instead of dihexa (***p .001)