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PARP1 Poly (ADP-ribose) polymerase 1, PKM2 Pyruvate kinase M2, RAS Renin-angiotensin system, CDT Chemodynamic therapy, ICD Immunogenic cell death, MR Magnetic resonance, PD-L1 Programmed death-ligand 1, RAGE Receptor for advanced glycation end-products, ROS Reactive oxygen species, KRAS Kirsten rat sarcoma viral oncogene, siRNA Small interfering RNA, ECM Extracellular matrix, NF- B Nuclear factor kappa B, AMPK Adenosine monophosphate-activated protein kinase, mTOR Mammalian target of rapamycin, miRNA34a MicroRNA 34a, GSK3 Glycogen synthase kinase-3, -TrCP Beta-transducin repeat-containing protein, LinTT1 Linear TT1, TAT Trans-activator of transcription Exosomes, small extracellular vesicles derived from various cell types, hold unique properties that make them promising tools for lung cancer diagnosis and treatment

Cells were fixed with 4% formaldehyde in 1 PBS for 10 min at room temperature

[vii] - Pace GW, Leaf CD

The FDA-approved formulations (Mounjaro and Zepbound) contain only tirzepatide as the active pharmaceutical ingredient and do not include vitamin B12

PMC Dimet-Wiley A.L