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Statements Acknowledgments We apologize for not being able to cite many relevant original papers, replaced by reviews, due to space limitation

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In vitro experiments have shown that SAMe increases the antiviral effect of interferon

Conclusion: Using a translational approach to identify novel biomarkers mechanistically related to the dynamics of collagen synthesis, we developed a blood-based biomarker panel with three biomarkers which is able to identify MASH patients with mild (F0/F1) or advanced (F3/F4) hepatic fibrosis with high accuracy

They are primarily used as adjunct therapy to levodopa to reduce motor fluctuations, particularly the wearingoff phenomenon [3, 6]